Automated 3D mapping of baseline and 12-month associations between three verbal memory measures and hippocampal atrophy in 490 ADNI subjects

LG Apostolova, JH Morra, AE Green, KS Hwang… - Neuroimage, 2010 - Elsevier
We used a previously validated automated machine learning algorithm based on adaptive
boosting to segment the hippocampi in baseline and 12-month follow-up 3D T1-weighted
brain MRIs of 150 cognitively normal elderly (NC), 245 mild cognitive impairment (MCI) and
97 Dementia of the Alzheimer's type (DAT) ADNI subjects. Using the radial distance
mapping technique, we examined the hippocampal correlates of delayed recall performance
on three well-established verbal memory tests—ADAScog delayed recall (ADAScog-DR) …
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